100% remote role
**Please Note: Applicants must be legally authorized to work in the United States. Sponsorship for employment visas is not available. Why Work With Us?At Candel, our people drive our success. We value diversity, collaboration, and bold thinking in a supportive, mission-driven environment. Like a team, we show up for each other and stay focused on making a difference for patients and families. Our leadership is transparent and empowering, and our culture is built on trust, flexibility, and accountability, encouraging ownership and innovation every day.
Our Science: Advancing Cancer Immunotherapies
Candel is a clinical-stage biopharma company developing off-the-shelf, multimodal immunotherapies that stimulate personalized, systemic anti-tumor responses. Our platforms use genetically modified adenovirus and HSV constructs. With positive Phase 3 results for our lead candidate, it’s an exciting time to join us and help bring transformative cancer treatments to patients. Learn more:
Position Summary:
Ready to make a meaningful impact in oncology from day one? This is a highly visible, hands-on role in designing, analyzing, and interpreting clinical trials that advance cancer therapeutics. This role is ideal for a highly motivated early-career biostatistician with a passion for applying statistical rigor to real-world oncology breakthroughs. You'll play a central role in supporting pivotal studies, including contributing to a Biologics License Application (BLA) for our lead immunotherapy candidate.
Reporting directly to the Senior Director of Biostatistics, you’ll gain mentorship and early ownership of high-impact work in a collaborative, lean team environment. You’ll thrive in a culture that values initiative, growth, and scientific integrity. If you're looking for real responsibility, real mentorship, and real impact—this is your moment.
What You Will Do:
Collaborate with cross-functional teams (clinical, regulatory, data management, programming) to design and analyze clinical trials.
Contribute to the development of statistical analysis plans (SAPs), including endpoints, estimands, and interim/final analysis strategies.
Perform statistical analyses using SAS or R and interpret results in the context of clinical relevance.
Support regulatory submissions (e.g., IND, NDA, BLA) and respond to health authority queries.
Participate in protocol development, case report form (CRF) design, and data review activities.
Ensure compliance with IBCH-GCP, CDISC, and internal SOPs.
Present statistical findings to internal stakeholders and external collaborators.
What You Will Bring:
PhD in Biostatistics, Statistics, or related field (MS with strong experience may be considered).
1–2 years of experience managing clinical trials in the pharmaceutical, biotech, or CRO industry.
Experience in oncology clinical trials is strongly preferred.
Proficiency in statistical programming (SAS required; R a plus).
Familiarity with regulatory guidance (FDA, EMA) and industry standards (CDISC, ICH).
Strong communication and collaboration skills.
Preferred Attributes:
Experience with adaptive trial designs, survival analysis, or Bayesian methods.
Exposure to early-phase oncology trials or biomarker-driven studies.
Ability to manage multiple priorities in a fast-paced environment.
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